Technology

CO2 Fractional Laser Devices (2026)

21 devices tracked · Resurfacing, Tattoo & Vascular

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All 21 co2 fractional laser systems, with pricing and FDA status

		Subcategory	Technology				Status
Alma	Hybrid	CO2 Fractional/Ablative	CO2 10600nm + 1570nm fiber hybrid	2021	$120k–$160k	$70k–$100k	CurrentFDA Cleared
Alma	Pixel CO2	CO2 Fractional/Ablative	Fractional CO2 pixel scanner	2009	—	$12k–$25k	Legacy-used-marketFDA Cleared
Candela	CO2RE	CO2 Fractional/Ablative	Fractional CO2 10600nm dual-ring scanning	2011	$90k–$120k	$25k–$45k	CurrentFDA Cleared
Cynosure	MonaLisa Touch	Fractional CO2 (gynecologic)	DEKA SmartXide fractional CO2 with intravaginal probe	2015	$100k–$140k	$20k–$50k	CurrentFDA Cleared
Cynosure	SmartSkin+	CO2 Fractional/Ablative	Fractional CO2 (El.En.-built)	2010	—	$15k–$30k	DiscontinuedFDA Cleared
Cynosure Lutronic	eCO2 3D	CO2 Fractional/Ablative	CO2 fractional resurfacing laser	—	—	—	CurrentFDA Cleared
DEKA	HELIX	CO2 Fractional/Ablative	Combined CO2 and non-ablative resurfacing platform	—	—	—	CurrentFDA Cleared
DEKA	SmartXide DOT	CO2 Fractional/Ablative	Fractional CO2 10600nm DOT therapy	2007	—	$12k–$25k	Legacy-used-marketFDA Cleared
DEKA	SmartXide2 DOT/RF	CO2 Fractional/Ablative	Fractional CO2 + bipolar RF	2011	—	$20k–$40k	Legacy-used-marketFDA Cleared
DEKA	SmartXide Punto	CO2 Fractional/Ablative	Compact fractional CO2	2020	$60k–$90k	—	CurrentFDA Cleared
DEKA	SmartXide Tetra PRO (CoolPeel)	CO2 Fractional/Ablative	Fractional CO2 with ultrashort H-pulse	2019	$90k–$125k	$45k–$70k	CurrentFDA Cleared
Lasering USA	MiXto SX	CO2 Fractional/Ablative	Fractional CO2 microspot scanner	2008	—	$10k–$22k	Legacy-used-marketFDA Cleared
Lumenis	AcuPulse	CO2 Fractional/Ablative	CO2 10600nm fractional (SuperPulse)	2010	$90k–$130k	$25k–$50k	CurrentFDA Cleared
Lumenis	AcuPulse DUO	CO2 Fractional/Ablative	CO2 10600nm fractional + surgical	2021	$100k–$140k	—	CurrentFDA Cleared
Lumenis	UltraPulse Alpha	CO2 Fractional/Ablative	CO2 10600nm high-energy fractional	2019	$150k–$200k	$70k–$110k	CurrentFDA Cleared
Lumenis	UltraPulse DUO	CO2 Fractional/Ablative	CO2 10600nm surgical + aesthetic	2015	—	$35k–$65k	DiscontinuedFDA Cleared
Lumenis	UltraPulse Encore	CO2 Fractional/Ablative	CO2 10600nm fractional + fully ablative (ActiveFX/DeepFX/TotalFX)	2006	—	$25k–$55k	Legacy-used-marketFDA Cleared
Lutronic	eCO2 Plus	CO2 Fractional/Ablative	Fractional CO2 with dual-depth microbeams	2014	$70k–$100k	$30k–$50k	CurrentFDA Cleared
Quanta System	Youlaser MT	Hybrid Fractional	CO2 10600nm + 1540nm mixed tech	2016	$90k–$120k	$45k–$70k	CurrentFDA Cleared
Rohrer Aesthetics	Phoenix CO2	CO2 Fractional/Ablative	Fractional + fully ablative CO2	2015	$50k–$75k	$25k–$40k	CurrentRegistered — no device clearance identified
Solta Medical	Fraxel re:pair SST	CO2 Fractional/Ablative	Fractional ablative CO2 10600nm	2008	—	$15k–$30k	DiscontinuedFDA Cleared

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Showing 21 of 21 matching devices (21 in this set).

CO2 Fractional Laser head-to-head comparisons

CO2RE vs SmartXide Tetra PRO CO2RE vs UltraPulse Alpha

Parent categories for CO2 Fractional Laser

Resurfacing, Tattoo & Vascular

Frequently asked questions

How many co2 fractional laser devices are tracked?: We track 21 co2 fractional laser platforms sold in the US, each with FDA status, published price ranges where we have them, and recorded chain adoption.
How much does a co2 fractional laser machine cost?: Across the 11 co2 fractional laser devices with a published new range, our researched US market pricing runs $50k–$200k. These are researched market ranges, not manufacturer quotes; each device profile carries its own source note.
Are co2 fractional laser devices FDA cleared?: 20 of the 21 co2 fractional laser devices we track carry a 510(k) clearance we have evidenced. FDA status is per device and per indication, so check the individual profile before relying on it.
Can you buy co2 fractional laser devices used?: We publish a used asking range for 17 of the 21 co2 fractional laser devices we track. Used asking ranges are observed market asks, not transaction prices.