Head to head

CO2RE vs Fraxis Duo (2026)

Compare purchase costs, running costs and the evidence behind each device.

Read the comparison overview

Purchase cost: Catalog new-price ranges: CO2RE, $90k–$120k; Fraxis Duo, $60k–$90k. Check the source notes and request current quotes.
Technology: CO2RE: CO2 fractional. Fraxis Duo: RF Microneedling.
Practice fit: Both are listed under CO2 fractional/ablative. Check each model’s US regulatory status and labeled indications for your intended use.

Device A

CO2 Fractional/Ablative

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Device B

CO2 Fractional/Ablative

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Price comparison

Price comparison: Candela CO2RE vs ilooda Fraxis Duo
Attribute	Candela CO2RE	ilooda Fraxis Duo
New price range	$90k–$120kSource not documented	$60k–$90kSource not documented
Used asking range	$25k–$45kSource not documented	Not published
Payback calculator	View ROI calculator	View ROI calculator
Next step

New price range

Candela CO2RE: $90k–$120kSource not documented
ilooda Fraxis Duo: $60k–$90kSource not documented

Used asking range

Candela CO2RE: $25k–$45kSource not documented
ilooda Fraxis Duo: Not published

Payback calculator

Candela CO2RE: View ROI calculator
ilooda Fraxis Duo: View ROI calculator

Next step

Candela CO2RE

ilooda Fraxis Duo

Consumable economics

Consumable economics: Candela CO2RE vs ilooda Fraxis Duo
Attribute	Candela CO2RE	ilooda Fraxis Duo
Consumable cost / lock-in	Supply pricing is not documented with a dated source yet. Request an itemized supply quote.	Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
Service cost	Not published	Not published

Consumable cost / lock-in

Candela CO2RE: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
ilooda Fraxis Duo: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.

Service cost

Candela CO2RE: Not published
ilooda Fraxis Duo: Not published

FDA clearance

FDA clearance: Candela CO2RE vs ilooda Fraxis Duo
Attribute	Candela CO2RE	ilooda Fraxis Duo
FDA status & indication	FDA ClearedK151655, K181523 Read FDA indication wording “The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”	FDA ClearedK160312 Read FDA indication wording “CO2 Laser part: Fractional mode is indicated only for ablative skin resurfacing. Non-fractional mode is indicated for incision, excision, ablation, vaporization and coagulation of body soft tissues including intraoral tissues, in medical specialties including aesthetic (dermatology and plastic surgery), otorhinolaryngology (ENT), gynecology, neurosurgery, dental and oral surgery and genitourinary surgery. HF electrosurgical part: The FRAXIS DUO is intended for use in dermatologic and general surgical procedures for electro-coagulation and hemostasis.”

FDA status & indication

Candela CO2RE: FDA ClearedK151655, K181523
Read FDA indication wording
“The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”
ilooda Fraxis Duo: FDA ClearedK160312
Read FDA indication wording
“CO2 Laser part: Fractional mode is indicated only for ablative skin resurfacing. Non-fractional mode is indicated for incision, excision, ablation, vaporization and coagulation of body soft tissues including intraoral tissues, in medical specialties including aesthetic (dermatology and plastic surgery), otorhinolaryngology (ENT), gynecology, neurosurgery, dental and oral surgery and genitourinary surgery. HF electrosurgical part: The FRAXIS DUO is intended for use in dermatologic and general surgical procedures for electro-coagulation and hemostasis.”

Which chains run each

Which chains run each: Candela CO2RE vs ilooda Fraxis Duo
Attribute	Candela CO2RE	ilooda Fraxis Duo
Chain adoption	0 recorded pairings	0 recorded pairings
Chains using it	—	—
Approved reviews	0	0

Chain adoption

Candela CO2RE: 0 recorded pairings
ilooda Fraxis Duo: 0 recorded pairings

Chains using it

Candela CO2RE: —
ilooda Fraxis Duo: —

Approved reviews

Candela CO2RE: 0
ilooda Fraxis Duo: 0

Specs and platform

Specs and platform: Candela CO2RE vs ilooda Fraxis Duo
Attribute	Candela CO2RE	ilooda Fraxis Duo
Manufacturer	Candela	ilooda
Built by (OEM)	Syneron Medical Ltd.	Ilooda Co., Ltd.
Category	CO2 Fractional/Ablative	CO2 Fractional/Ablative
Technology	Fractional CO2 10600nm dual-ring scanning (CO2 fractional)	Fractional CO2 + RF microneedling (RF Microneedling)
Launch year	2011	2017
Status	Current	Current
Manufacturer source record	No linked source on file.	No linked source on file.

Manufacturer

Candela CO2RE: Candela
ilooda Fraxis Duo: ilooda

Built by (OEM)

Candela CO2RE: Syneron Medical Ltd.
ilooda Fraxis Duo: Ilooda Co., Ltd.

Current alternatives

Current catalog models in related categories. Confirm availability and configuration with the supplier.

Rohrer Aesthetics Phoenix CO2

CO2 Fractional/Ablative

New: $59,995 (Rohrer-advertised price)

Lumenis AcuPulse

CO2 Fractional/Ablative

New: $90k–$130k

DEKA SmartXide Punto

CO2 Fractional/Ablative

New: $60k–$90k

DEKA HELIX

CO2 Fractional/Ablative

New: —

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