Cynosure PicoSure Pro
Picosecond Tattoo/Pigment · 755nm picosecond alexandrite (higher energy)
The Cynosure PicoSure Pro typically sells new in the $100k–$140k range in the US, with used and refurbished systems around $60k–$95k. Cynosure PicoSure Pro holds FDA 510(k) clearance for its marketed indication. Figures are market estimates verified August 6, 2026.
What it's actually cleared for: Tattoo removal; benign pigmented lesions incl. Nevus of Ota, Hori's macules, melasma pigment; acne scars and wrinkles (I-IV) with Focus array
Last verified: August 6, 2026 · How we verify
New: $100k–$140k|Used: $60k–$95kmarket estimate, no email required
| Manufacturer | Cynosure |
|---|---|
| Company | Owner: Hahn & Company (South Korean private equity) (private equity owned, since 2024) · Distribution: direct |
| Category | Resurfacing, Tattoo & Vascular |
| Technology | 755nm picosecond alexandrite (higher energy) |
| FDA status | FDA Cleared |
| New price range | $100k–$140k |
| Used price range | $60k–$95k |
| Consumables | Not published |
| Launch year | 2022 |
| Last verified | August 6, 2026 |
Bottom line
The brand-name king of picosecond lasers — the 755nm alexandrite platform with the strongest consumer awareness in tattoo removal and pigment, refreshed in 2022 with higher energy plus FDA-cleared melasma-pigment labeling competitors can't match at 755nm. You pay for it: ~$150k-250k new and Cynosure's notoriously expensive service contracts are the real cost of ownership. A destination device that can anchor a practice's pigment/tattoo identity — the math works with strong local demand and marketing muscle. Factor Cynosure's post-merger restructuring into your service-risk assessment.
Overview
Current-gen PicoSure with 1064 add-on
How it works
The science
A picosecond 755nm alexandrite (with optional 532/1064nm delivery) firing ultra-short pulses that create a photomechanical — not photothermal — effect: pigment and ink shattered by pressure rather than cooked by heat, better fragmentation with less collateral thermal injury than nanosecond lasers. 755nm is strongly absorbed by melanin: efficient on brown/black pigment, sunspots, Nevus of Ota, Hori's macules, and stubborn green/blue ink. With the Focus lens array, the same energy creates laser-induced optical breakdown (LIOB) vacuoles in the epidermis that remodel skin for acne scars, wrinkles, and revitalization with minimal downtime.
Patented tech
PressureWave is Cynosure's trademark for the 755nm picosecond photomechanical delivery; the Focus lens array concentrates energy into micro-zones for revitalization without ablation; the Pro upgrade added higher peak energy and the melasma-pigment clearance Cynosure markets as a world-first. A very well-executed pico alexandrite with a real clinical paper trail.
Origin
Cynosure, Westford, Massachusetts, USA (Cynosure Lutronic since 2024).
FDA & regulatory status
What it's actually cleared for:
Tattoo removal; benign pigmented lesions incl. Nevus of Ota, Hori's macules, melasma pigment; acne scars and wrinkles (I-IV) with Focus array
510(k) numbers
K210226
Regulatory data is compiled from public FDA 510(k) records and may lag recent clearances. Always confirm status with the manufacturer before purchase.
Recent industry events
How we source company dataOwnership and corporate changes at Cynosure that can affect warranty, service and parts availability.
- Jan 2024
Cynosure and Lutronic merge under Hahn & Company
MergerCynosure and Lutronic announced their merger on January 19, 2024, closing later that year to form Cynosure Lutronic, Inc. under South Korean private equity firm Hahn & Company; terms undisclosed. This followed CD&R's 2019 purchase of Cynosure from Hologic for $205M and Hahn's 2023 acquisition of Lutronic.
Source: PR Newswire (Jan 19, 2024); Hologic filings
Treatment economics
What practices charge
Focus revitalization $400-900 with series of 3-4 at $1,200-3,000; melasma protocols 3-6 sessions at $500-900 each; tattoo removal $300-800+ per session by size over 5-10 sessions — the pico premium supports 20-40% higher pricing than Q-switched competitors.
Consumables & recurring cost
No true per-treatment consumable — but the alexandrite architecture means periodic lamp/laser-head service, and Cynosure contracts at $15k-25k+/year function as the de facto consumable. An out-of-warranty pico repair can run five figures per incident.
Ideal for
Best-fit practice
Practices building a pigment/tattoo center of gravity or premium no-downtime revitalization menu — urban markets with tattoo density, Asian and Hispanic patient bases with melasma/Hori's demand, patients 25-60 who search the PicoSure brand by name. Overkill for occasional sunspot touch-ups.
Compliance
Medical director & delegation
Class II laser; delegation to RNs/NPs/PAs or certified laser techs under a medical director is common but state-dependent; several states restrict who may fire Class IV aesthetic lasers.
Contraindications & screening
Pregnancy, active infection, recent tanning (melanin competition at 755nm), photosensitizers, gold salts, isotretinoin history; darker Fitzpatrick work often shifts to the 1064nm handpiece — 755nm carries more epidermal melanin risk.
Ownership
Warranty & service
1-year standard then costly contracts ($15k-25k+); field-service reputation uneven through the merger period — demand written SLAs and loaner terms.
Resale & used market
The most liquid pico on the secondary market thanks to brand demand — used PicoSure/Pro trade actively at $60k-120k depending on year, config, and service eligibility; contract transferability is the key resale variable.
Chains using this device
No confirmed chain deployments recorded yet.
Owner reviews
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Alternatives
Head-to-head comparisons buyers ask for
History
Every tracked change to pricing, lifecycle status, FDA data and warranty terms — newest first.
August 5, 2026
FDA K-numbers
K210226; K133364 → K210226
Source: Automatic record update
August 5, 2026
FDA indication
Picosecond 755nm laser cleared for tattoo removal, benign pigmented lesions, acne scars and wrinkles → Tattoo removal; benign pigmented lesions incl. Nevus of Ota, Hori's macules, melasma pigment; acne scars and wrinkles (I-IV) with Focus array
Source: Automatic record update
August 5, 2026
FDA K-numbers
K210226 → K210226; K133364
Source: Automatic record update
August 5, 2026
FDA indication
Tattoo removal; benign pigmented lesions incl. Nevus of Ota, Hori's macules, melasma pigment; acne scars and wrinkles (I-IV) with Focus array → Picosecond 755nm laser cleared for tattoo removal, benign pigmented lesions, acne scars and wrinkles
Source: Automatic record update
August 1, 2026
Record created
Added to The Aesthetic Index — August 2026
Source: The Aesthetic Index editorial
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