Head to head

enlighten III vs PicoSure Pro (2026)

Compare purchase costs, running costs and the evidence behind each device.

Read the comparison overview

Purchase cost: Catalog new-price ranges: enlighten III, $90k–$130k; PicoSure Pro, $100k–$140k. Check the source notes and request current quotes.
Technology: enlighten III: Picosecond. PicoSure Pro: Alexandrite.
Practice fit: Both are listed under picosecond tattoo/pigment. Check each model’s US regulatory status and labeled indications for your intended use.

Device A

Picosecond Tattoo/Pigment

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Device B

Picosecond Tattoo/Pigment

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Price comparison

Price comparison: Cutera enlighten III vs Cynosure PicoSure Pro
Attribute	Cutera enlighten III	Cynosure PicoSure Pro
New price range	$90k–$130kSource not documented	$100k–$140kReported source: Dealer quote · Aug 12, 2026
Used asking range	$40k–$65kSource not documented	$60k–$95kReported source: Used listing · Aug 12, 2026
Payback calculator	View ROI calculator	View ROI calculator
Next step

New price range

Cutera enlighten III: $90k–$130kSource not documented
Cynosure PicoSure Pro: $100k–$140kReported source: Dealer quote · Aug 12, 2026

Used asking range

Cutera enlighten III: $40k–$65kSource not documented
Cynosure PicoSure Pro: $60k–$95kReported source: Used listing · Aug 12, 2026

Payback calculator

Cutera enlighten III: View ROI calculator
Cynosure PicoSure Pro: View ROI calculator

Next step

Cutera enlighten III

Cynosure PicoSure Pro

Consumable economics

Consumable economics: Cutera enlighten III vs Cynosure PicoSure Pro
Attribute	Cutera enlighten III	Cynosure PicoSure Pro
Consumable cost / lock-in	Supply pricing is not documented with a dated source yet. Request an itemized supply quote.	No true per-treatment consumable — but the alexandrite architecture means periodic lamp/laser-head service, and the Cynosure service contract functions as the de facto consumable. Contract and out-of-warranty repair pricing are not published — get them in writing before you sign.
Service cost	Not published	Not published

Consumable cost / lock-in

Cutera enlighten III: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
Cynosure PicoSure Pro: No true per-treatment consumable — but the alexandrite architecture means periodic lamp/laser-head service, and the Cynosure service contract functions as the de facto consumable. Contract and out-of-warranty repair pricing are not published — get them in writing before you sign.

Service cost

Cutera enlighten III: Not published
Cynosure PicoSure Pro: Not published

FDA clearance

FDA clearance: Cutera enlighten III vs Cynosure PicoSure Pro
Attribute	Cutera enlighten III	Cynosure PicoSure Pro
FDA status & indication	FDA ClearedK160488, K172077, K182997 Read FDA indication wording “The enlighten III laser system is intended for use in surgical and aesthetic applications in the medical specialties of dermatology and general and plastic surgery. 1064 nm: The 1064 nm wavelength of the enlighten III laser system is indicated for: • treatment of benign pigmented lesions on patients with all skin types (Fitzpatrick I-VI) • tattoo removal for dark colored tattoo inks and for multicolored tattoos containing dark colored tattoo inks on patients with all skin types (Fitzpatrick I-VI) 532 nm: The 532 nm wavelength of the enlighten III laser system is indicated for: • treatment of benign pigmented lesions on patients with Fitzpatrick skin types I-III • tattoo removal for lighter colored tattoo inks, including red and yellow inks, on patients with Fitzpatrick skin types I-III 670 nm: The 670 nm wavelength of the enlighten III laser system is indicated for treatment of benign pigmented lesions on patients with Fitzpatrick skin types I-III.”	FDA ClearedK210226 Read FDA indication wording “PicoSure Workstation (K210226) PicoSure Workstation (K173199) RevLite Q-Switched Nd:YAG Laser System (K133254) 755nm: The PicoSure Workstation is indicated for tattoo and benign pigmented lesions removal including but not limited to: Nevus of Ota, Hori macules (nevus of Hori), and Melasma. The PicoSure Workstation with the 2mm and 6mm hand pieces and the Focus Array are indicated for the treatment of acne scars and wrinkles in Skin Types I – IV. 532nm: The PicoSure 532-nm delivery system is indicated for tattoo removal and benign pigmented lesions removal in Skin Types I- III. 1064nm: The PicoSure 1064-nm delivery system is indicated for tattoo and benign pigmented lesions removal. 755 nm: The PicoSure Workstation is indicated for tattoo and benign pigmented lesions removal. The PicoSure Workstation with the 2mm and 6mm handpieces and the Focus Array are indicated for the treatment of acne scars and wrinkles in Skin Types I-IV. 532 nm: The PicoSure 532 nm Laser Delivery System is indicated for tattoo removal and benign pigmented lesion removal in Skin Types I-III. 1064 nm: The PicoSure 1064 nm Laser Delivery System is indicated for tattoo and benign pigmented lesions removal. 1064 nm: Tattoo Removal (dark ink: blue and black) Dermal Pigmented Lesions; including but not limited to; Nevus of Ota, Lentigines, Nevi, Melasma and Café-au-lait Removal or lightening of hair with or without adjuvant preparation.”

FDA status & indication

Cutera enlighten III: FDA ClearedK160488, K172077, K182997
Read FDA indication wording
“The enlighten III laser system is intended for use in surgical and aesthetic applications in the medical specialties of dermatology and general and plastic surgery. 1064 nm: The 1064 nm wavelength of the enlighten III laser system is indicated for: • treatment of benign pigmented lesions on patients with all skin types (Fitzpatrick I-VI) • tattoo removal for dark colored tattoo inks and for multicolored tattoos containing dark colored tattoo inks on patients with all skin types (Fitzpatrick I-VI) 532 nm: The 532 nm wavelength of the enlighten III laser system is indicated for: • treatment of benign pigmented lesions on patients with Fitzpatrick skin types I-III • tattoo removal for lighter colored tattoo inks, including red and yellow inks, on patients with Fitzpatrick skin types I-III 670 nm: The 670 nm wavelength of the enlighten III laser system is indicated for treatment of benign pigmented lesions on patients with Fitzpatrick skin types I-III.”
Cynosure PicoSure Pro: FDA ClearedK210226
Read FDA indication wording
“PicoSure Workstation (K210226) PicoSure Workstation (K173199) RevLite Q-Switched Nd:YAG Laser System (K133254) 755nm: The PicoSure Workstation is indicated for tattoo and benign pigmented lesions removal including but not limited to: Nevus of Ota, Hori macules (nevus of Hori), and Melasma. The PicoSure Workstation with the 2mm and 6mm hand pieces and the Focus Array are indicated for the treatment of acne scars and wrinkles in Skin Types I – IV. 532nm: The PicoSure 532-nm delivery system is indicated for tattoo removal and benign pigmented lesions removal in Skin Types I- III. 1064nm: The PicoSure 1064-nm delivery system is indicated for tattoo and benign pigmented lesions removal. 755 nm: The PicoSure Workstation is indicated for tattoo and benign pigmented lesions removal. The PicoSure Workstation with the 2mm and 6mm handpieces and the Focus Array are indicated for the treatment of acne scars and wrinkles in Skin Types I-IV. 532 nm: The PicoSure 532 nm Laser Delivery System is indicated for tattoo removal and benign pigmented lesion removal in Skin Types I-III. 1064 nm: The PicoSure 1064 nm Laser Delivery System is indicated for tattoo and benign pigmented lesions removal. 1064 nm: Tattoo Removal (dark ink: blue and black) Dermal Pigmented Lesions; including but not limited to; Nevus of Ota, Lentigines, Nevi, Melasma and Café-au-lait Removal or lightening of hair with or without adjuvant preparation.”

Which chains run each

Which chains run each: Cutera enlighten III vs Cynosure PicoSure Pro
Attribute	Cutera enlighten III	Cynosure PicoSure Pro
Chain adoption	0 recorded pairings	0 recorded pairings
Chains using it	—	—
Approved reviews	0	0

Chain adoption

Cutera enlighten III: 0 recorded pairings
Cynosure PicoSure Pro: 0 recorded pairings

Chains using it

Cutera enlighten III: —
Cynosure PicoSure Pro: —

Approved reviews

Cutera enlighten III: 0
Cynosure PicoSure Pro: 0

Specs and platform

Specs and platform: Cutera enlighten III vs Cynosure PicoSure Pro
Attribute	Cutera enlighten III	Cynosure PicoSure Pro
Manufacturer	Cutera	Cynosure
Built by (OEM)	Cutera Inc.	Cynosure LLC
Category	Picosecond Tattoo/Pigment	Picosecond Tattoo/Pigment
Technology	532/670/1064nm pico+nano (Picosecond)	755nm picosecond alexandrite (higher energy) (Alexandrite)
Launch year	2017	2022
Status	Current	Current
Manufacturer source record	No linked source on file.	No linked source on file.

Manufacturer

Cutera enlighten III: Cutera
Cynosure PicoSure Pro: Cynosure

Built by (OEM)

Cutera enlighten III: Cutera Inc.
Cynosure PicoSure Pro: Cynosure LLC

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