Head to head

CO2RE vs eCO2 Plus (2026)

Compare purchase costs, running costs and the evidence behind each device.

Read the comparison overview

Purchase cost: Catalog new-price ranges: CO2RE, $90k–$120k; eCO2 Plus, $70k–$100k. Check the source notes and request current quotes.
Practice fit: Both are listed under CO2 fractional/ablative. Check each model’s US regulatory status and labeled indications for your intended use.

Device A

CO2 Fractional/Ablative

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Device B

CO2 Fractional/Ablative

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Price comparison

Price comparison: Candela CO2RE vs Lutronic eCO2 Plus
Attribute	Candela CO2RE	Lutronic eCO2 Plus
New price range	$90k–$120kSource not documented	$70k–$100kSource not documented
Used asking range	$25k–$45kSource not documented	$30k–$50kSource not documented
Payback calculator	View ROI calculator	View ROI calculator
Next step

New price range

Candela CO2RE: $90k–$120kSource not documented
Lutronic eCO2 Plus: $70k–$100kSource not documented

Used asking range

Candela CO2RE: $25k–$45kSource not documented
Lutronic eCO2 Plus: $30k–$50kSource not documented

Payback calculator

Candela CO2RE: View ROI calculator
Lutronic eCO2 Plus: View ROI calculator

Next step

Candela CO2RE

Lutronic eCO2 Plus

Consumable economics

Consumable economics: Candela CO2RE vs Lutronic eCO2 Plus
Attribute	Candela CO2RE	Lutronic eCO2 Plus
Consumable cost / lock-in	Supply pricing is not documented with a dated source yet. Request an itemized supply quote.	—
Service cost	Not published	Not published

Consumable cost / lock-in

Candela CO2RE: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
Lutronic eCO2 Plus: —

Service cost

Candela CO2RE: Not published
Lutronic eCO2 Plus: Not published

FDA clearance

FDA clearance: Candela CO2RE vs Lutronic eCO2 Plus
Attribute	Candela CO2RE	Lutronic eCO2 Plus
FDA status & indication	FDA ClearedK151655, K181523 Read FDA indication wording “The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”	FDA ClearedK100610 Read FDA indication wording “The eCO2 Plus Laser System with fractionated handpieces is indicated for use in dermatological procedures requiring ablation (removal), resurfacing and coagulation of soft tissue. Additionally, the 120 micron and 300 micron spot sizes are used in the treatment of wrinkles; rhytides, furrows, fine lines, textural irregularities, pigmented lesions and vascular dyschromia. The eCO2 Plus Laser System using the non-fractionated handpieces (F100, F50, and Zoom) is also indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: dermatology, plastic surgery, podiatry, neurosurgery, gynecology, otorhinolaryngology (ENT), arthroscopy (knee), and open endoscopic general surgery. Dermatology & Plastic Surgery — The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: • Laser skin resurfacing • Treatment of wrinkles, rhytids and furrows • Ablation and/or vaporization of soft tissue in dermatology and plastic surgery for the reduction, removal, and/or treatment of actinic keratosis, skin tags, solar/actinic elastosis, actinic cheilitis, lentigines, uneven pigmentation/dyschromia, acne scars, surgical scars, keloids, hemangiomas (including buccal […]”

FDA status & indication

Candela CO2RE: FDA ClearedK151655, K181523
Read FDA indication wording
“The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”
Lutronic eCO2 Plus: FDA ClearedK100610
Read FDA indication wording
“The eCO2 Plus Laser System with fractionated handpieces is indicated for use in dermatological procedures requiring ablation (removal), resurfacing and coagulation of soft tissue. Additionally, the 120 micron and 300 micron spot sizes are used in the treatment of wrinkles; rhytides, furrows, fine lines, textural irregularities, pigmented lesions and vascular dyschromia. The eCO2 Plus Laser System using the non-fractionated handpieces (F100, F50, and Zoom) is also indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: dermatology, plastic surgery, podiatry, neurosurgery, gynecology, otorhinolaryngology (ENT), arthroscopy (knee), and open endoscopic general surgery. Dermatology & Plastic Surgery — The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: • Laser skin resurfacing • Treatment of wrinkles, rhytids and furrows • Ablation and/or vaporization of soft tissue in dermatology and plastic surgery for the reduction, removal, and/or treatment of actinic keratosis, skin tags, solar/actinic elastosis, actinic cheilitis, lentigines, uneven pigmentation/dyschromia, acne scars, surgical scars, keloids, hemangiomas (including buccal […]”

Which chains run each

Which chains run each: Candela CO2RE vs Lutronic eCO2 Plus
Attribute	Candela CO2RE	Lutronic eCO2 Plus
Chain adoption	0 recorded pairings	0 recorded pairings
Chains using it	—	—
Approved reviews	0	0

Chain adoption

Candela CO2RE: 0 recorded pairings
Lutronic eCO2 Plus: 0 recorded pairings

Chains using it

Candela CO2RE: —
Lutronic eCO2 Plus: —

Approved reviews

Candela CO2RE: 0
Lutronic eCO2 Plus: 0

Specs and platform

Specs and platform: Candela CO2RE vs Lutronic eCO2 Plus
Attribute	Candela CO2RE	Lutronic eCO2 Plus
Manufacturer	Candela	Lutronic
Built by (OEM)	Syneron Medical Ltd.	Lutronic Corporation
Category	CO2 Fractional/Ablative	CO2 Fractional/Ablative
Technology	Fractional CO2 10600nm dual-ring scanning (CO2 fractional)	Fractional CO2 with dual-depth microbeams (CO2 fractional)
Launch year	2011	2014
Status	Current	Current
Manufacturer source record	No linked source on file.	No linked source on file.

Manufacturer

Candela CO2RE: Candela
Lutronic eCO2 Plus: Lutronic

Built by (OEM)

Candela CO2RE: Syneron Medical Ltd.
Lutronic eCO2 Plus: Lutronic Corporation

Current alternatives

Current catalog models in related categories. Confirm availability and configuration with the supplier.

Rohrer Aesthetics Phoenix CO2

CO2 Fractional/Ablative

New: $59,995 (Rohrer-advertised price)

Lumenis AcuPulse

CO2 Fractional/Ablative

New: $90k–$130k

DEKA SmartXide Punto

CO2 Fractional/Ablative

New: $60k–$90k

DEKA HELIX

CO2 Fractional/Ablative

New: —

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