Head to head

CO2RE vs UltraPulse Encore (2026)

Compare purchase costs, running costs and the evidence behind each device.

Read the comparison overview

Purchase cost: The catalog lists $90k–$120k for CO2RE. No new-price range is on file for UltraPulse Encore. Check the source notes and request current quotes.
Practice fit: Both are listed under CO2 fractional/ablative. Check each model’s US regulatory status and labeled indications for your intended use.

Device A

CO2 Fractional/Ablative

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Device B

CO2 Fractional/Ablative

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Price comparison

Price comparison: Candela CO2RE vs Lumenis UltraPulse Encore
Attribute	Candela CO2RE	Lumenis UltraPulse Encore
New price range	$90k–$120kSource not documented	Not published
Used asking range	$25k–$45kSource not documented	$25k–$55kSource not documented
Payback calculator	View ROI calculator	View ROI calculator
Next step		Explore this model’s specs and owner reviews. For new-equipment inquiries, browse current models. Browse current models

New price range

Candela CO2RE: $90k–$120kSource not documented
Lumenis UltraPulse Encore: Not published

Used asking range

Candela CO2RE: $25k–$45kSource not documented
Lumenis UltraPulse Encore: $25k–$55kSource not documented

Payback calculator

Candela CO2RE: View ROI calculator
Lumenis UltraPulse Encore: View ROI calculator

Next step

Candela CO2RE

Lumenis UltraPulse Encore

Explore this model’s specs and owner reviews. For new-equipment inquiries, browse current models.

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Consumable economics

Consumable economics: Candela CO2RE vs Lumenis UltraPulse Encore
Attribute	Candela CO2RE	Lumenis UltraPulse Encore
Consumable cost / lock-in	Supply pricing is not documented with a dated source yet. Request an itemized supply quote.	Mode-dependent: ActiveFX and PigmentFX run through the reusable UltraScan CPG with no per-treatment tip, while DeepFX and DeepFX Air consume a single-use distance-gauge spacer every case (GUDID: single-use).
Service cost	Not published	Not published

Consumable cost / lock-in

Candela CO2RE: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
Lumenis UltraPulse Encore: Mode-dependent: ActiveFX and PigmentFX run through the reusable UltraScan CPG with no per-treatment tip, while DeepFX and DeepFX Air consume a single-use distance-gauge spacer every case (GUDID: single-use).

Service cost

Candela CO2RE: Not published
Lumenis UltraPulse Encore: Not published

FDA clearance

FDA clearance: Candela CO2RE vs Lumenis UltraPulse Encore
Attribute	Candela CO2RE	Lumenis UltraPulse Encore
FDA status & indication	FDA ClearedK151655, K181523 Read FDA indication wording “The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”	FDA ClearedK022060 Read FDA indication wording “Lumenis UltraPulse Encore Carbon Dioxide Surgical Lasers (and their delivery accessories) are used to deliver light energy and are indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic (dermatology and plastic surgery), podiatry, otolaryngology (ENT), gynecology (including laparoscopy), neurosurgery, orthopedics (soft tissue), arthroscopy (knee), general and thoracic surgery (including open and endoscopic), dental and oral surgery and genitourinary surgery. In addition, the Lumenis UltraPulse Encore Carbon Dioxide Surgical Lasers are safe and effective when indicated for use in specific surgical applications in medical specialties including: aesthetic (dermatology and plastic surgery), podiatry, otolaryngology (ENT), gynecology (including laparoscopy), neurosurgery, orthopedics (soft tissue), arthroscopy (knee), general and thoracic surgery (including open and endoscopic), dental and oral surgery and genitourinary surgery.”

FDA status & indication

Candela CO2RE: FDA ClearedK151655, K181523
Read FDA indication wording
“The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”
Lumenis UltraPulse Encore: FDA ClearedK022060
Read FDA indication wording
“Lumenis UltraPulse Encore Carbon Dioxide Surgical Lasers (and their delivery accessories) are used to deliver light energy and are indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic (dermatology and plastic surgery), podiatry, otolaryngology (ENT), gynecology (including laparoscopy), neurosurgery, orthopedics (soft tissue), arthroscopy (knee), general and thoracic surgery (including open and endoscopic), dental and oral surgery and genitourinary surgery. In addition, the Lumenis UltraPulse Encore Carbon Dioxide Surgical Lasers are safe and effective when indicated for use in specific surgical applications in medical specialties including: aesthetic (dermatology and plastic surgery), podiatry, otolaryngology (ENT), gynecology (including laparoscopy), neurosurgery, orthopedics (soft tissue), arthroscopy (knee), general and thoracic surgery (including open and endoscopic), dental and oral surgery and genitourinary surgery.”

Which chains run each

Which chains run each: Candela CO2RE vs Lumenis UltraPulse Encore
Attribute	Candela CO2RE	Lumenis UltraPulse Encore
Chain adoption	0 recorded pairings	0 recorded pairings
Chains using it	—	—
Approved reviews	0	0

Chain adoption

Candela CO2RE: 0 recorded pairings
Lumenis UltraPulse Encore: 0 recorded pairings

Chains using it

Candela CO2RE: —
Lumenis UltraPulse Encore: —

Approved reviews

Candela CO2RE: 0
Lumenis UltraPulse Encore: 0

Specs and platform

Specs and platform: Candela CO2RE vs Lumenis UltraPulse Encore
Attribute	Candela CO2RE	Lumenis UltraPulse Encore
Manufacturer	Candela	Lumenis
Built by (OEM)	Syneron Medical Ltd.	Lumenis Be Ltd.
Category	CO2 Fractional/Ablative	CO2 Fractional/Ablative
Technology	Fractional CO2 10600nm dual-ring scanning (CO2 fractional)	CO2 10600nm fractional + fully ablative (ActiveFX/DeepFX/TotalFX) (CO2 fractional)
Launch year	2011	2006
Status	Current	Legacy-used-market
Manufacturer source record	No linked source on file.	No linked source on file.

Manufacturer

Candela CO2RE: Candela
Lumenis UltraPulse Encore: Lumenis

Built by (OEM)

Candela CO2RE: Syneron Medical Ltd.
Lumenis UltraPulse Encore: Lumenis Be Ltd.

Current alternatives

Current catalog models in related categories. Confirm availability and configuration with the supplier.

Rohrer Aesthetics Phoenix CO2

CO2 Fractional/Ablative

New: $59,995 (Rohrer-advertised price)

Lumenis AcuPulse

CO2 Fractional/Ablative

New: $90k–$130k

DEKA SmartXide Punto

CO2 Fractional/Ablative

New: $60k–$90k

DEKA HELIX

CO2 Fractional/Ablative

New: —

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