Head to head

CO2RE vs SmartXide2 DOT (2026)

Compare purchase costs, running costs and the evidence behind each device.

Read the comparison overview

Purchase cost: The catalog lists $90k–$120k for CO2RE. No new-price range is on file for SmartXide2 DOT. Check the source notes and request current quotes.
Practice fit: Both are listed under CO2 fractional/ablative. Check each model’s US regulatory status and labeled indications for your intended use.

Device A

CO2 Fractional/Ablative

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Device B

CO2 Fractional/Ablative

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Price comparison

Price comparison: Candela CO2RE vs DEKA SmartXide2 DOT/RF
Attribute	Candela CO2RE	DEKA SmartXide2 DOT/RF
New price range	$90k–$120kSource not documented	Not published
Used asking range	$25k–$45kSource not documented	$20k–$40kSource not documented
Payback calculator	View ROI calculator	View ROI calculator
Next step		Explore this model’s specs and owner reviews. For new-equipment inquiries, browse current models. Browse current models

New price range

Candela CO2RE: $90k–$120kSource not documented
DEKA SmartXide2 DOT/RF: Not published

Used asking range

Candela CO2RE: $25k–$45kSource not documented
DEKA SmartXide2 DOT/RF: $20k–$40kSource not documented

Payback calculator

Candela CO2RE: View ROI calculator
DEKA SmartXide2 DOT/RF: View ROI calculator

Next step

Candela CO2RE

DEKA SmartXide2 DOT/RF

Explore this model’s specs and owner reviews. For new-equipment inquiries, browse current models.

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Consumable economics

Consumable economics: Candela CO2RE vs DEKA SmartXide2 DOT/RF
Attribute	Candela CO2RE	DEKA SmartXide2 DOT/RF
Consumable cost / lock-in	Supply pricing is not documented with a dated source yet. Request an itemized supply quote.	—
Service cost	Not published	Not published

Consumable cost / lock-in

Candela CO2RE: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
DEKA SmartXide2 DOT/RF: —

Service cost

Candela CO2RE: Not published
DEKA SmartXide2 DOT/RF: Not published

FDA clearance

FDA clearance: Candela CO2RE vs DEKA SmartXide2 DOT/RF
Attribute	Candela CO2RE	DEKA SmartXide2 DOT/RF
FDA status & indication	FDA ClearedK151655, K181523 Read FDA indication wording “The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”	FDA ClearedK113504 Read FDA indication wording “The DEKA SmartXide 2 CO2 laser is indicated for incision, excision, ablation, vaporization, and coagulation of body soft tissues in medical specialties including aesthetic (dermatology and plastic surgery), podiatry, otolaryngology (ENT), gynaecology, neurosurgery, orthopaedics, general and thoracic surgery (including open and endoscopic), dental and oral surgery and genitourinary surgery. The DEKA Smartide 2940nm diode laser is indicated for incision, excision, vaporization ablation and coagulation of soft tissues (open surgery), cutting, vaporization, ablation and coagulation of soft tissues (endoscopic surgery) in medical specialties including: plastic surgery, dermatology, ENT, gynaecology, urology, general surgery, gastroenterology and dental procedures. The DEKA SmartXide 2 980nm diode laser is indicated for incision, excision, vaporization ablation and coagulation of soft tissues (open and endoscopic surgery) in medical specialties including plastic surgery, dermatology, ear, nose and throat and oral surgery (otolaryngology), gynaecology, urology, neurosurgery, general and thoracic surgery, gastroenterology and dental procedures. .Comparison:The DEKA SmartXide 2 laser system with its delivery accessories is substantially equivalent to its predicate devices. It shares same indication for use, same principle of operation and essentially same technological characteristics and performances.”

FDA status & indication

Candela CO2RE: FDA ClearedK151655, K181523
Read FDA indication wording
“The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”
DEKA SmartXide2 DOT/RF: FDA ClearedK113504
Read FDA indication wording
“The DEKA SmartXide 2 CO2 laser is indicated for incision, excision, ablation, vaporization, and coagulation of body soft tissues in medical specialties including aesthetic (dermatology and plastic surgery), podiatry, otolaryngology (ENT), gynaecology, neurosurgery, orthopaedics, general and thoracic surgery (including open and endoscopic), dental and oral surgery and genitourinary surgery. The DEKA Smartide 2940nm diode laser is indicated for incision, excision, vaporization ablation and coagulation of soft tissues (open surgery), cutting, vaporization, ablation and coagulation of soft tissues (endoscopic surgery) in medical specialties including: plastic surgery, dermatology, ENT, gynaecology, urology, general surgery, gastroenterology and dental procedures. The DEKA SmartXide 2 980nm diode laser is indicated for incision, excision, vaporization ablation and coagulation of soft tissues (open and endoscopic surgery) in medical specialties including plastic surgery, dermatology, ear, nose and throat and oral surgery (otolaryngology), gynaecology, urology, neurosurgery, general and thoracic surgery, gastroenterology and dental procedures. .Comparison:The DEKA SmartXide 2 laser system with its delivery accessories is substantially equivalent to its predicate devices. It shares same indication for use, same principle of operation and essentially same technological characteristics and performances.”

Which chains run each

Which chains run each: Candela CO2RE vs DEKA SmartXide2 DOT/RF
Attribute	Candela CO2RE	DEKA SmartXide2 DOT/RF
Chain adoption	0 recorded pairings	0 recorded pairings
Chains using it	—	—
Approved reviews	0	0

Chain adoption

Candela CO2RE: 0 recorded pairings
DEKA SmartXide2 DOT/RF: 0 recorded pairings

Chains using it

Candela CO2RE: —
DEKA SmartXide2 DOT/RF: —

Approved reviews

Candela CO2RE: 0
DEKA SmartXide2 DOT/RF: 0

Specs and platform

Specs and platform: Candela CO2RE vs DEKA SmartXide2 DOT/RF
Attribute	Candela CO2RE	DEKA SmartXide2 DOT/RF
Manufacturer	Candela	DEKA
Built by (OEM)	Syneron Medical Ltd.	DEKA M.E.L.A. S.r.l.
Category	CO2 Fractional/Ablative	CO2 Fractional/Ablative
Technology	Fractional CO2 10600nm dual-ring scanning (CO2 fractional)	Fractional CO2 + bipolar RF (CO2 fractional)
Launch year	2011	2011
Status	Current	Legacy-used-market
Manufacturer source record	No linked source on file.	No linked source on file.

Manufacturer

Candela CO2RE: Candela
DEKA SmartXide2 DOT/RF: DEKA

Built by (OEM)

Candela CO2RE: Syneron Medical Ltd.
DEKA SmartXide2 DOT/RF: DEKA M.E.L.A. S.r.l.

Current alternatives

Current catalog models in related categories. Confirm availability and configuration with the supplier.

Rohrer Aesthetics Phoenix CO2

CO2 Fractional/Ablative

New: $59,995 (Rohrer-advertised price)

Lumenis AcuPulse

CO2 Fractional/Ablative

New: $90k–$130k

DEKA SmartXide Punto

CO2 Fractional/Ablative

New: $60k–$90k

DEKA HELIX

CO2 Fractional/Ablative

New: —

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