Head to head

CO2RE vs eCO2 3D (2026)

Compare purchase costs, running costs and the evidence behind each device.

Read the comparison overview

Purchase cost: No new-price range is on file for either CO2RE or eCO2 3D. Request current quotes to compare purchase costs.
Practice fit: Both are listed under CO2 fractional/ablative. Check each model’s US regulatory status and labeled indications for your intended use.

Device A

CO2 Fractional/Ablative

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Device B

CO2 Fractional/Ablative

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Price comparison

Price comparison: Candela CO2RE vs Cynosure Lutronic eCO2 3D
Attribute	Candela CO2RE	Cynosure Lutronic eCO2 3D
New price range	Not published	Not published
Used price reference	$25k–$45kSource not documented	Not published
Payback calculator	View ROI calculator	View cost details
Next step

New price range

Candela CO2RE: Not published
Cynosure Lutronic eCO2 3D: Not published

Used price reference

Candela CO2RE: $25k–$45kSource not documented
Cynosure Lutronic eCO2 3D: Not published

Payback calculator

Candela CO2RE: View ROI calculator
Cynosure Lutronic eCO2 3D: View cost details

Next step

Candela CO2RE

Cynosure Lutronic eCO2 3D

Supplies & running costs

Supplies & running costs: Candela CO2RE vs Cynosure Lutronic eCO2 3D
Attribute	Candela CO2RE	Cynosure Lutronic eCO2 3D
Supplies & restrictions	Supply pricing is not documented with a dated source yet. Request an itemized supply quote. View running-cost details	Supply details not yet documented. View running-cost details

Supplies & restrictions

Candela CO2RE: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
View running-cost details
Cynosure Lutronic eCO2 3D: Supply details not yet documented.
View running-cost details

FDA status & indications

FDA status & indications: Candela CO2RE vs Cynosure Lutronic eCO2 3D
Attribute	Candela CO2RE	Cynosure Lutronic eCO2 3D
FDA status & indication	FDA record cited — see scopeK151655, K181523 Record scope: K181523 names the CO2RE Laser System and includes separate standard, fractional and surgical handpiece indications. K151655 is the earlier cited platform record. Included handpieces and applicable labeling determine scope; a platform clearance is not a statement that every accessory is supplied. Read FDA indication wording “The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”	FDA record cited — see scopeK244060 Record scope: 510(k): K244060 (decision 31 Jul 2025). Checked 4 Sep 2026. Read FDA indication wording “The eCO2 3D Laser System with fractional handpieces is indicated for use in dermatological procedures requiring ablation (removal), resurfacing and coagulation of soft tissue. Additionally, the 120 micron and 300 micron spot sizes are used in the treatment of wrinkles; rhytides, furrows, fine lines, textural irregularities, pigmented lesions and vascular dyschromia. The eCO2 3D Laser System using the non-fractional handpieces (F100, F50, Zoom, and 500 micron tip) is also indicated for use in skin resurfacing and surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: dermatology, plastic surgery, and podiatry. Dermatology & Plastic Surgery: The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: * Laser skin resurfacing * Treatment of wrinkles, rhytids and furrows * Ablation and/or vaporization of soft tissue in dermatology and plastic surgery for the reduction, removal, and/or treatment of actinic keratosis, skin tags, solar/actinic elastosis, actinic cheilitis, lentigines, uneven pigmentation/dyschromia, acne scars, surgical scars, keloids, hemangiomas (including buccal hemangiomas), tattoos, telangiectasia, squamous and basal cell carcinoma, spider and epidermal naevi, xanthelasma palpebrarum, syringoma, and verrucae and seborrhoecae vulgares (warts); laser derm-ablation; and laser burn debridement. Dermatology. Plastic Surgery & General Surgery: Laser incision and/or excision of soft tissue in dermatology, plastic and general surgery, including the performance of blepharoplasty and for the creation of recipient sites for hair transplantation, treatment of hemorrhoids, atheroma, cysts, abscesses, and all other soft tissue applications. Podiatry: Laser ablation, vaporization, and/or excision of soft tissue in podiatry for the reduction, removal, and/or treatment of verrucae vulgares.”

FDA status & indication

Candela CO2RE: FDA record cited — see scopeK151655, K181523
Record scope: K181523 names the CO2RE Laser System and includes separate standard, fractional and surgical handpiece indications. K151655 is the earlier cited platform record. Included handpieces and applicable labeling determine scope; a platform clearance is not a statement that every accessory is supplied.
Read FDA indication wording
“The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”
Cynosure Lutronic eCO2 3D: FDA record cited — see scopeK244060
Record scope: 510(k): K244060 (decision 31 Jul 2025). Checked 4 Sep 2026.
Read FDA indication wording
“The eCO2 3D Laser System with fractional handpieces is indicated for use in dermatological procedures requiring ablation (removal), resurfacing and coagulation of soft tissue. Additionally, the 120 micron and 300 micron spot sizes are used in the treatment of wrinkles; rhytides, furrows, fine lines, textural irregularities, pigmented lesions and vascular dyschromia. The eCO2 3D Laser System using the non-fractional handpieces (F100, F50, Zoom, and 500 micron tip) is also indicated for use in skin resurfacing and surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: dermatology, plastic surgery, and podiatry. Dermatology & Plastic Surgery: The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: * Laser skin resurfacing * Treatment of wrinkles, rhytids and furrows * Ablation and/or vaporization of soft tissue in dermatology and plastic surgery for the reduction, removal, and/or treatment of actinic keratosis, skin tags, solar/actinic elastosis, actinic cheilitis, lentigines, uneven pigmentation/dyschromia, acne scars, surgical scars, keloids, hemangiomas (including buccal hemangiomas), tattoos, telangiectasia, squamous and basal cell carcinoma, spider and epidermal naevi, xanthelasma palpebrarum, syringoma, and verrucae and seborrhoecae vulgares (warts); laser derm-ablation; and laser burn debridement. Dermatology. Plastic Surgery & General Surgery: Laser incision and/or excision of soft tissue in dermatology, plastic and general surgery, including the performance of blepharoplasty and for the creation of recipient sites for hair transplantation, treatment of hemorrhoids, atheroma, cysts, abscesses, and all other soft tissue applications. Podiatry: Laser ablation, vaporization, and/or excision of soft tissue in podiatry for the reduction, removal, and/or treatment of verrucae vulgares.”

Which chains run each

Which chains run each: Candela CO2RE vs Cynosure Lutronic eCO2 3D
Attribute	Candela CO2RE	Cynosure Lutronic eCO2 3D
Chain adoption	0 recorded pairings	0 recorded pairings
Chains using it	—	—
Approved reviews	0	0

Chain adoption

Candela CO2RE: 0 recorded pairings
Cynosure Lutronic eCO2 3D: 0 recorded pairings

Chains using it

Candela CO2RE: —
Cynosure Lutronic eCO2 3D: —

Approved reviews

Candela CO2RE: 0
Cynosure Lutronic eCO2 3D: 0

Specs and platform

Specs and platform: Candela CO2RE vs Cynosure Lutronic eCO2 3D
Attribute	Candela CO2RE	Cynosure Lutronic eCO2 3D
Manufacturer	Candela	Cynosure Lutronic
Built by (OEM)	Syneron Medical Ltd.	Cynosure LLC
Category	CO2 Fractional/Ablative	CO2 Fractional/Ablative
Technology	Fractional CO2 10600nm dual-ring scanning (CO2 fractional)	CO2 fractional resurfacing laser (CO2 fractional)
Launch year	2011	—
Status	Current	Current
Manufacturing relationship evidence	No separate manufacturing-relationship record linked.	No separate manufacturing-relationship record linked.

Manufacturer

Candela CO2RE: Candela
Cynosure Lutronic eCO2 3D: Cynosure Lutronic

Built by (OEM)

Candela CO2RE: Syneron Medical Ltd.
Cynosure Lutronic eCO2 3D: Cynosure LLC

Current alternatives

Current catalog models in related categories. Confirm availability and configuration with the supplier.

Alma Hybrid

CO2 Fractional/Ablative

New-equipment price not yet documented.

DEKA HELIX

CO2 Fractional/Ablative

New-equipment price not yet documented.

DEKA SmartXide Punto

CO2 Fractional/Ablative

New-equipment price reference

$60k–$90k

Source not documented

Check the profile for configuration and price details.

DEKA SmartXide Tetra PRO (CoolPeel)

CO2 Fractional/Ablative

New-equipment price reference

$90k–$125k

Source not documented

Check the profile for configuration and price details.

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