Head to head

Pixel CO2 vs CO2RE (2026)

Compare purchase costs, running costs and the evidence behind each device.

Read the comparison overview

Purchase cost: The catalog lists $90k–$120k for CO2RE. No new-price range is on file for Pixel CO2. Check the source notes and request current quotes.
Practice fit: Both are listed under CO2 fractional/ablative. Check each model’s US regulatory status and labeled indications for your intended use.

Device A

CO2 Fractional/Ablative

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Device B

CO2 Fractional/Ablative

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Price comparison

Price comparison: Alma Pixel CO2 vs Candela CO2RE
Attribute	Alma Pixel CO2	Candela CO2RE
New price range	Not published	$90k–$120kSource not documented
Used asking range	$12k–$25kSource not documented	$25k–$45kSource not documented
Payback calculator	View ROI calculator	View ROI calculator
Next step	Explore this model’s specs and owner reviews. For new-equipment inquiries, browse current models. Browse current models

New price range

Alma Pixel CO2: Not published
Candela CO2RE: $90k–$120kSource not documented

Used asking range

Alma Pixel CO2: $12k–$25kSource not documented
Candela CO2RE: $25k–$45kSource not documented

Payback calculator

Alma Pixel CO2: View ROI calculator
Candela CO2RE: View ROI calculator

Next step

Alma Pixel CO2

Explore this model’s specs and owner reviews. For new-equipment inquiries, browse current models.

Browse current models

Candela CO2RE

Consumable economics

Consumable economics: Alma Pixel CO2 vs Candela CO2RE
Attribute	Alma Pixel CO2	Candela CO2RE
Consumable cost / lock-in	—	Supply pricing is not documented with a dated source yet. Request an itemized supply quote.
Service cost	Not published	Not published

Consumable cost / lock-in

Alma Pixel CO2: —
Candela CO2RE: Supply pricing is not documented with a dated source yet. Request an itemized supply quote.

Service cost

Alma Pixel CO2: Not published
Candela CO2RE: Not published

FDA clearance

FDA clearance: Alma Pixel CO2 vs Candela CO2RE
Attribute	Alma Pixel CO2	Candela CO2RE
FDA status & indication	FDA ClearedK103501, K250071 Read FDA indication wording “The Alma Lasers Pixel CO2TM Laser System, Delivery Devices and Accessories are intended for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The Alma Lasers Pixel CO2TM Laser System is cleared for use for the particular indications as folIlows: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of:- * laser skin resurfacing * laser derm-abrasion * laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of:, * wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows With CO2 laser increases the amount of sub-epidermal collagen.”	FDA ClearedK151655, K181523 Read FDA indication wording “The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”

FDA status & indication

Alma Pixel CO2: FDA ClearedK103501, K250071
Read FDA indication wording
“The Alma Lasers Pixel CO2TM Laser System, Delivery Devices and Accessories are intended for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The Alma Lasers Pixel CO2TM Laser System is cleared for use for the particular indications as folIlows: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of:- * laser skin resurfacing * laser derm-abrasion * laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of:, * wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows With CO2 laser increases the amount of sub-epidermal collagen.”
Candela CO2RE: FDA ClearedK151655, K181523
Read FDA indication wording
“The CO2RE is indicated for use in surgical applications requiring the ablation, vaporization, excision, incision, and coagulation of soft tissue in medical specialties including: aesthetic surgery (dermatology and plastic surgery), podiatry, gynecology, neurosurgery, orthopedics (soft tissue), arthroscopy (knee). The CO2RE is indicated for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin. The Standard Handpiece of the CO2RE System is indicated for the following: Dermatology & Plastic Surgery The ablation, vaporization, excision, incision, and coagulation of soft tissue in dermatology and plastic surgery in the performance of: x laser skin resurfacing x laser dermabrasion x laser burn debridement. Laser skin resurfacing (ablation and/or vaporization) for the treatment of: x wrinkles, rhytids, and furrows (including fines lines and texture irregularities) Clinical literature demonstrates that skin resurfacing of wrinkles, rhytids, and furrows with CO2 laser increases the amount of sub-epidermal collagen.”

Which chains run each

Which chains run each: Alma Pixel CO2 vs Candela CO2RE
Attribute	Alma Pixel CO2	Candela CO2RE
Chain adoption	0 recorded pairings	0 recorded pairings
Chains using it	—	—
Approved reviews	0	0

Chain adoption

Alma Pixel CO2: 0 recorded pairings
Candela CO2RE: 0 recorded pairings

Chains using it

Alma Pixel CO2: —
Candela CO2RE: —

Approved reviews

Alma Pixel CO2: 0
Candela CO2RE: 0

Specs and platform

Specs and platform: Alma Pixel CO2 vs Candela CO2RE
Attribute	Alma Pixel CO2	Candela CO2RE
Manufacturer	Alma	Candela
Built by (OEM)	Alma Lasers Ltd.	Syneron Medical Ltd.
Category	CO2 Fractional/Ablative	CO2 Fractional/Ablative
Technology	Fractional CO2 pixel scanner (CO2 fractional)	Fractional CO2 10600nm dual-ring scanning (CO2 fractional)
Launch year	2009	2011
Status	Legacy-used-market	Current
Manufacturer source record	No linked source on file.	No linked source on file.

Manufacturer

Alma Pixel CO2: Alma
Candela CO2RE: Candela

Built by (OEM)

Alma Pixel CO2: Alma Lasers Ltd.
Candela CO2RE: Syneron Medical Ltd.

Current alternatives

Current catalog models in related categories. Confirm availability and configuration with the supplier.

Rohrer Aesthetics Phoenix CO2

CO2 Fractional/Ablative

New: $59,995 (Rohrer-advertised price)

Lumenis AcuPulse

CO2 Fractional/Ablative

New: $90k–$130k

DEKA SmartXide Punto

CO2 Fractional/Ablative

New: $60k–$90k

DEKA HELIX

CO2 Fractional/Ablative

New: —

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